Lecture notes

Utilization of ketone bodies and ketosis- lecture 3

Utilization of ketone bodies The ketone bodies are water-soluble and are transported across the inner mitochondrial membrane as well as across the blood-brain barrier and cell membranes. Thus, they can be used as a fuel source by a variety of tissues, including the CNS. They are preferred substrates for aerobic muscle and heart, thus sparing […]

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Alcohol Induced Metabolic Changes- A Case Study

Case details A 65-year-old man was admitted to the emergency department in an unconscious state. Apparently, he had become increasingly depressed after the death of his younger son two months ago. Previously, before his death, he had been a moderate drinker, but consumption of alcohol had increased markedly over the last few weeks. He had

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Minor pathways of oxidation of fatty acids- Lecture-2 (omega and peroxisomal oxidation)

Omega oxidation of fatty acids Another minor pathway for fatty acid oxidation also involves hydroxylation and occurs in the endoplasmic reticulum of many tissues. In this case, hydroxylation takes place on the methyl carbon at the other end of the molecule from the carboxyl group or on the carbon next to the methyl end. It

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